Invokana Side Effects: Kidney Damage, UTI, and Ketoacidosis

Invokana Side Effects: Kidney Damage, UTI, and Ketoacidosis. What are the Invokana side effects that patients using the Type 2 diabetes drug should be aware of? The more common side effects include the following:

  • urinary tract infections
  • increased urination
  • yeast infections
  • vaginal itching
  • thirst
  • constipation
  • nausea
  • fatigue
  • weakness
  • skin sensitivity to sunlight and
  • hypersensitivity reactions (including skin redness, rash, itching, hives, and swelling)
  • bladder pain
  • bloody or cloudy urine
  • decreased frequency or amount of urine
  • difficult, burning, or painful urination
  • discharge with a strong odor from the p*n*s
  • frequent urge to urinate
  • increased thirst
  • itching of the v*g*na or outside of the g*n*t*ls
  • loss of appetite
  • lower back or side pain
  • nausea
  • pain during s*xual intercourse
  • pain in the skin around the p*n*s
  • redness, itching, or swelling of the p*n*s
  • swelling of the face, fingers, or lower legs
  • troubled breathing
  • unusual tiredness or weakness
  • v*g*n*l discharge without odor or with mild odor
  • vomiting
  • weight gain

invokana side effects - kidney damage ketoacidosis and uti

Last March 2016, the Food and Drug Administration strengthened its warning about the kidney damage that could result from Invokana use. From the agency’s media release:

Based on recent reports, we have revised the warnings in the drug labels to include information about acute kidney injury and added recommendations to minimize this risk.

Patients should seek medical attention immediately if they experience signs and symptoms of acute kidney injury. This is a serious condition in which the kidneys suddenly stop working, causing dangerous levels of wastes to build up in the body. Signs and symptoms of acute kidney injury may include decreased urine or swelling in the legs or feet. Patients should not stop taking their medicine without first talking to their health care professionals. Doing so can lead to uncontrolled blood sugar levels that can be harmful.

It is worth noting that Johnson and Johnson, which manufactures Invokana, is facing lawsuits filed by patients who developed ketoacidosis from using the drug.

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